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EpCAM antibody [EGP40/1110]

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691
Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691
Anti-EpCAM antibody [EGP40/1110] used in Protein Array (Protein Array). GTX34691
Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691
Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691
Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

Cat. No. GTX34691

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 EGP40/1110

Isotype

 IgG2b

Application

 IHC-P, Protein Array

Reactivity

 Human, Mouse, Rat
Package
100 μg ($529)
See all EpCAM products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 min at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A recombinant fragment from the cytoplasmic domain (around aa 280-350) of human EpCAM (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DIAR5 , EGP2 , EGP314 , EGP40 , EPCAM , ESA , HNPCC8 , KS1/4 , KSA , M4S1 , MIC18 , MK1 , TACSTD1 , TROP1 , epithelial cell adhesion molecule , EpCAM , CD326

Cellular Localization

Lateral cell membrane,Cell junction,Tight junction

Background

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Database

Research Area

DATA IMAGES

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

GTX34691 IHC-P Image

IHC-P analysis of rat colon tissue using GTX34691 EpCAM antibody [EGP40/1110].

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

GTX34691 IHC-P Image

IHC-P analysis of human ovarian carcinoma tissue using GTX34691 EpCAM antibody [EGP40/1110].

Anti-EpCAM antibody [EGP40/1110] used in Protein Array (Protein Array). GTX34691

GTX34691 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using EpCAM Mouse Monoclonal Antibody (EGP40/1110). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

GTX34691 IHC-P Image

IHC-P analysis of rat lung tissue using GTX34691 EpCAM antibody [EGP40/1110].

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

GTX34691 IHC-P Image

IHC-P analysis of mouse colon tissue using GTX34691 EpCAM antibody [EGP40/1110].

Anti-EpCAM antibody [EGP40/1110] used in IHC (Paraffin sections) (IHC-P). GTX34691

GTX34691 IHC-P Image

IHC-P analysis of rat oviduct tissue using GTX34691 EpCAM antibody [EGP40/1110].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529