GeneTex
  • Country / Location Selection

United States (US)

EpCAM antibody

Anti-EpCAM antibody used in IHC (Paraffin sections) (IHC-P). GTX34690
Anti-EpCAM antibody used in IHC (Paraffin sections) (IHC-P). GTX34690

Cat No. GTX34690

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
Package
100 μg ($429)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1ug/ml
ICC/IF 1-2ug/ml
IHC-P 1-2ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Specificity/Sensitivity

EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. Ep-CAM antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. Ep-CAM antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
PROPERTIES

Form

Liquid

Buffer

10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human TACSTD1 protein

Purification

Ab purified by Protein A

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Epithelial Cell Adhesion Molecule,Diar5,Egp-2,Egp314,Egp40,Esa,Hnpcc8,Ks1/4,Ksa,M4S1,Mic18,Mk-1,Tacstd1,Trop1,Epcam

Background

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Database

Research Area

DATA IMAGES
Anti-EpCAM antibody used in IHC (Paraffin sections) (IHC-P). GTX34690

GTX34690 IHC-P Image

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Ep-CAM Rabbit Polyclonal Antibody.

Anti-EpCAM antibody used in IHC (Paraffin sections) (IHC-P). GTX34690

GTX34690 IHC-P Image

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Ep-CAM Rabbit Polyclonal Antibody.

REFERENCE
There are currently no references for EpCAM antibody (GTX34690). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for EpCAM antibody (GTX34690). Be the first to share your experience with this product.
Package List Price ($)
$ 429