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Ephrin A2 (cleaved Asn188) antibody

Anti-Ephrin A2 (cleaved Asn188) antibody used in Western Blot (WB). GTX86940

Cat. No. GTX86940

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Ephrin A2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

Ephrin A2 (cleaved Asn188) antibody detects endogenous levels of fragment of activated EFNA2 resulting from cleavage adjacent to Asn188.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Ephrin A2 (139-188).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

EFNA2 , ELF1 , EPLG6 , HEK7L , LERK6 , ephrin A2 , Ephrin A2 , ephrin-A2

Cellular Localization

Cell membrane

Background

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ephrin A2 (cleaved Asn188) antibody used in Western Blot (WB). GTX86940

GTX86940 WB Image

WB analysis of 293 cells treated with etoposide 25uM (1h) lysate using GTX86940 Ephrin A2 (cleaved Asn188) antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399