GeneTex
United States (US)

Eps15 antibody [C3], C-term

GTX108486_39812_WB_19011507_235.jpg
GTX108486_39812_WB_M_19011507_893.jpg

Cat No. GTX108486

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

Raji , K562 , BCL-1

Predict Reactivity

Bovine, Chicken(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.83 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Eps15. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Epidermal Growth Factor Receptor Pathway Substrate 15,Af-1P,Af1P,Mllt5,Eps15

Cellular Localization

Cytoplasm , Cell membrane; Peripheral membrane protein; Cytoplasmic side , Isoform 2: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side

Background

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX108486_39812_WB_19011507_235.jpg

GTX108486 WB Image

Sample (30 ug of whole cell lysate)
A: Raji
B: K562
5% SDS PAGE
GTX108486 diluted at 1:1000

GTX108486_39812_WB_M_19011507_893.jpg

GTX108486 WB Image

Sample (30 ug of whole cell lysate)
A: BCL-1
5% SDS PAGE
GTX 108486 diluted at 1:500

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169