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Estrogen Receptor alpha antibody [6F11] (ready-to-use)

Anti-Estrogen Receptor alpha antibody [6F11] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73808

Cat No. GTX73808

Host

Mouse

Clonality

Monoclonal

Clone Name

6F11

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
5 ml ($509)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:20-1:80

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.

Not tested in other applications.

Calculated MW

66 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the full-length estrogen receptor molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ER , ESR , ESR1 , ESRA , ESTRR , Era , NR3A1 , estrogen receptor 1 , ER alpha , Estrogen Receptor alpha

Cellular Localization

Nucleus,Cytoplasm,Cell membrane,Golgi apparatus

Background

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-Estrogen Receptor alpha antibody [6F11] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73808

GTX73808 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX73808 Estrogen Receptor alpha antibody [6F11] (ready-to-use).

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 509