*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Mouse, Rat(>80% identity)
PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide sequence around phosphorylation site of serine 106 (S-P- S(p)-P-L) derived from human Estrogen Receptor alpha.
Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
Cytoplasm,Cell membrane,Cell membrane; Single-pass type I membrane protein,Golgi apparatus
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
GTX50138 WB Image
WB analysis of extracts from MCF-7 cells untreated or treated with EGF using GTX50138 Estrogen Receptor alpha (phospho Ser106) antibody.
GTX50138 ICC/IF Image
ICC/IF analysis of methanol-fixed MCF cells using GTX50138 Estrogen Receptor alpha (phospho Ser106) antibody.
GTX50138 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX50138 Estrogen Receptor alpha (phospho Ser106) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide