APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:1000 |
| 1:50 - 1:100 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human Estrogen Receptor-α around the phosphorylation site of serine106 (S-P- Sp-P-L).
Purification
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum
Conjugation
Unconjugated
RRID
AB_11168454
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ER,ESR,ESR1,ESRA,ESTRR,Era,NR3A1,estrogen receptor 1,ER alpha,Estrogen Receptor alpha
Cellular Localization
Nucleus,Cytoplasm,Cell membrane,Golgi apparatus
Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Database
Research Area
DATA IMAGES
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GTX79082 WB Image
WB analysis of Estradiol treated MCF7 cell lysate using GTX79082 Estrogen Receptor alpha (phospho Ser106) antibody (Lane 3 and 4) and Estrogen Receptor alpha antibody (Lane 1 and 2).
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GTX79082 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX79082 Estrogen Receptor alpha (phospho Ser106) antibody.
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REFERENCE
There are currently no references for Estrogen Receptor alpha (phospho Ser106) antibody (GTX79082). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Estrogen Receptor alpha (phospho Ser106) antibody (GTX79082). Be the first to share your experience with this product.
