GeneTex

  • Country / Location Selection

United States (US)

Estrogen Receptor antibody [SP1]

Anti-Estrogen Receptor antibody [SP1] used in IHC (Paraffin sections) (IHC-P). GTX04736

Cat. No. GTX04736

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 SP1

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($1429)
See all Estrogen Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25-1:50

Note :

IHC-P
Recommendations for antigen retrieval : EDTA Buffer pH 8.0 at room temperature for 30 mins.
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

batch dependent

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide derived from C-terminal of human estrogen receptor.

Purification

Unpurified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ER,ESR,ESR1,ESRA,ESTRR,Era,NR3A1,estrogen receptor 1,ER alpha,Estrogen Receptor alpha

Cellular Localization

Nucleus,Cytoplasm,Cell membrane,Golgi apparatus

Background

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Database

Research Area

DATA IMAGES

Anti-Estrogen Receptor antibody [SP1] used in IHC (Paraffin sections) (IHC-P). GTX04736

GTX04736 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX04736 Estrogen Receptor antibody [SP1].
Antigen retrieval : EDTA Buffer pH 8.0

REFERENCE

There are currently no references for Estrogen Receptor antibody [SP1] (GTX04736). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Estrogen Receptor antibody [SP1] (GTX04736). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 1429