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Estrogen Receptor beta 2 antibody [57/3]

Anti-Estrogen Receptor beta 2 antibody [57/3] used in IHC (Paraffin sections) (IHC-P). GTX41214
Anti-Estrogen Receptor beta 2 antibody [57/3] used in IHC (Paraffin sections) (IHC-P). GTX41214

Cat. No. GTX41214

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 57/3

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($899)
See all Estrogen Receptor beta 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1/50-1/500

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose. Glycine/ EDTA preparations have also been used with success in some tissues
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Product Note

This antibody recognizes the estrogen receptor beta 2 isoform. No cross-reactivity is seen with estrogen receptor beta 1 isoform.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide derived from the C terminus of the human estrogen receptor beta 2 isoform, CGMKMETLLPEATMEQ.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

estrogen receptor 2 , ER-BETA , ESR-BETA , ESRB , ESTRB , Erb , NR3A2 , ODG8

Cellular Localization

Nucleus

Background

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Estrogen Receptor beta 2 antibody [57/3] used in IHC (Paraffin sections) (IHC-P). GTX41214

GTX41214 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX41214 Estrogen Receptor beta 2 antibody. Antigen retrieval using citrate buffer at pH6.2.

Anti-Estrogen Receptor beta 2 antibody [57/3] used in IHC (Paraffin sections) (IHC-P). GTX41214

GTX41214 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX41214 Estrogen Receptor beta 2 antibody. Antigen retrieval using citrate buffer at pH6.2.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 899