GeneTex
United States (US)

Estrogen Receptor beta antibody

GTX23577_2039_IHC-P_19011519_175.jpg
GTX23577_2027_ICC-IF_19011519_892.jpg

Cat No. GTX23577

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, ChIP assay, GSA
Reactivity Human, Mouse, Rat, Sheep, Bovine, Hamster, Pig, Primate
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2 μg/ml
ICC/IF 0.5-4 μg/ml
IHC-P 1-2 μg/mL
IHC-Fr 1-2 μg/mL
FACS Assay dependent
IP Assay dependent
ChIP assay Assay dependent
GSA 1-5 μl
Not tested in other applications.

Calculated MW

59 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 1mg/ml BSA, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat ER beta.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ER-BETA,ESR-BETA,ESRB,ESTRB,Erb,NR3A2

Cellular Localization

Nucleus

Background

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX23577_2039_IHC-P_19011519_175.jpg

GTX23577 IHC-P Image

IHC-P analysis of primate amygdala tissue using GTX23577 Estrogen Receptor beta antibody.

GTX23577_2027_ICC-IF_19011519_892.jpg

GTX23577 ICC/IF Image

ICC/IF analysis of cells using GTX23577 Estrogen Receptor beta antibody.

REFERENCE
Package List Price ($)
$ 299