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F2RL3 / PAR-4 (cleaved Gly48) antibody

Anti-F2RL3 / PAR-4 (cleaved Gly48) antibody used in Western Blot (WB). GTX86937

Cat. No. GTX86937

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse
Package
100 μg ($399)
See all F2RL3 / PAR-4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Product Note

F2RL3 / PAR-4 (cleaved Gly48) antibody detects endogenous levels of fragment of activated PAR4 resulting from cleavage adjacent to Gly48.

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human F2RL3 / PAR-4 (29-78).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

F2R like thrombin/trypsin receptor 3 , F2RL3 , PAR4 , PAR-4

Cellular Localization

Cell membrane

Background

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-F2RL3 / PAR-4 (cleaved Gly48) antibody used in Western Blot (WB). GTX86937

GTX86937 WB Image

WB analysis of NIH/3T3 cells treated with etoposide using GTX86937 F2RL3 / PAR-4 (cleaved Gly48) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399