APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1/500 - 1/2000 |
1/200 - 1/1000 |
1/200 - 1/400 |
1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human FAK expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein tyrosine kinase 2 , FADK , FAK , FAK1 , FRNK , PPP1R71 , p125FAK , pp125FAK
Cellular Localization
Cytoplasm, cytoskeleton,Nucleus
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]
Database
Research Area
DATA IMAGES
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GTX83323 ICC/IF Image
ICC/IF analysis of A549 cells using GTX83323 FAK antibody [10H7E9]. Green : FAK Blue: DRAQ5 fluorescent DNA dye
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GTX83323 WB Image
WB analysis of FAK(AA: 354-533)-hIgGFc transfected HEK293 cell lysate using GTX83323 FAK antibody [10H7E9].
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GTX83323 FACS Image
FACS analysis of Raji cells using GTX83323 FAK antibody [10H7E9]. Green : FAK Purple : negative control
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REFERENCE
There are currently no references for FAK antibody [10H7E9] (GTX83323). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for FAK antibody [10H7E9] (GTX83323). Be the first to share your experience with this product.