FAP antibody

Cat. No. GTX04307

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, FACS, ELISA
Reactivity	Human
Package	100 μg ($469)

See all FAP products

Datasheet

View product citations for antibody GTX04307 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	0.1-0.25 μg/mL
FACS	1-3 μg/106 cells
ELISA	0.1-0.5 μg/mL

Not tested in other applications.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4

Preservative

No preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E.coli-derived human Fibroblast activation protein, alpha/FAP recombinant protein (Position: Q65-Q580).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibroblast activation protein alpha , DPPIV , FAPA , FAPalpha , SIMP

Cellular Localization

Cell membrane , Membrane , Cytoplasm

Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Database

Gene ID: 2191 FAP
UniProt: Q12884 FAP

Research Area

DATA IMAGES

GTX04307 FACS Image

FACS analysis of SiHa cells using GTX04307 FAP antibody.
Dilution : 1μg/1x106 cells
Blue : Primary antibody
Green : Isotype control
Red : Unlabelled sample

GTX04307 WB Image

WB analysis of various cell lysates using GTX04307 FAP antibody.
Loading : 30 μg
Dilution : 0.25 μg/mL

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 469

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