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FBXL17 antibody [C1C3]

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in Western Blot (WB). GTX119211

Cat. No. GTX119211

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all FBXL17 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

MCF-7

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human FBXL17. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10618294

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

F-box and leucine rich repeat protein 17 , FBXO13 , Fbl17 , Fbx13

Background

Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse muscle.
FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse heart.
FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm in mouse testis by immunohistochemical analysis.
Sample: Paraffin-embedded mouse testis.
FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in Western Blot (WB). GTX119211

GTX119211 WB Image

Sample (30 ug of whole cell lysate)
A: MCF-7
10% SDS PAGE
GTX119211 diluted at 1:1000

REFERENCE

Application Reference

Mason B et al. Cell Mol Life Sci 2019; Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169