GeneTex
United States (US)

FBXO2 antibody [C2C3], C-term

GTX104858_WB_19011506_160.jpg
GTX104858_39694_IHC_19011506_753.jpg

Cat No. GTX104858

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

A431 , H1299 , HepG2

Predict Reactivity

Mouse, Rat, Bovine, Guinea pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FBXO2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

FBG1 antibody, FBX2 antibody, Fbs1 antibody, NFB42 antibody, OCP1 antibody, FBXO2 antibody, organ of Corti protein 1 antibody, F-box gene 1 antibody, F-box only protein 2 antibody, F-box protein 2 antibody

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq]

Database

DATA IMAGES
GTX104858_WB_19011506_160.jpg

GTX104858 WB Image

Sample (30 ug of whole cell lysate)
A: H1299
12% SDS PAGE
GTX104858 diluted at 1:1000

GTX104858_39694_IHC_19011506_753.jpg

GTX104858 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human adrenal gland tumor, using FBXO2(GTX104858) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169