GeneTex
United States (US)

FBXO32 antibody

GTX37381_20190129_IHC-P_19012901_854.jpg

Cat No. GTX37381

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 41-120 amino acids of human Fbx32

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

F-Box Protein 32,Fbx32,Mafbx,Fbxo32

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Database

DATA IMAGES
GTX37381_20190129_IHC-P_19012901_854.jpg

GTX37381 IHC-P Image

IHC-P analysis of rat uterus tissue using GTX37381 FBXO32 antibody.
Fixation : 4% PFA
Antigen retireval : boiling with citrate buffer
Dilution : 1:200

Package List Price ($)
$ 339