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FBXW11 antibody

Anti-FBXW11 antibody used in IHC (Paraffin sections) (IHC-P). GTX33193
Anti-FBXW11 antibody used in Western Blot (WB). GTX33193
Anti-FBXW11 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33193

Cat. No. GTX33193

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all FBXW11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FBXW11 (NP_387448.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

F-box and WD repeat domain containing 11 , BTRC2 , BTRCP2 , FBW1B , FBXW1B , Fbw11 , Hos

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-FBXW11 antibody used in IHC (Paraffin sections) (IHC-P). GTX33193

GTX33193 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX33193 FBXW11 antibody.
Dilution : 1:100

Anti-FBXW11 antibody used in Western Blot (WB). GTX33193

GTX33193 WB Image

WB analysis of various sample lysates using GTX33193 FBXW11 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-FBXW11 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33193

GTX33193 ICC/IF Image

ICC/IF analysis of A549 cells using GTX33193 FBXW11 antibody.

REFERENCE

Application Reference

SY Tsai et al. Cell Death Discov 2024; 10 (1) : 472 DDX3 is critical for female fertility via translational control in oogenesis
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419