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FCN1 antibody

Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195
Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195
Anti-FCN1 antibody used in Western Blot (WB). GTX33195
Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195

Cat. No. GTX33195

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all FCN1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-326 of human FCN1 (NP_001994.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887702

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ficolin 1 , FCNM

Cellular Localization

Secreted,Cell membrane

Background

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES

Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195

GTX33195 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX33195 FCN1 antibody.
Dilution : 1:100

Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195

GTX33195 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX33195 FCN1 antibody.
Dilution : 1:100

Anti-FCN1 antibody used in Western Blot (WB). GTX33195

GTX33195 WB Image

WB analysis of various sample lysates using GTX33195 FCN1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-FCN1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33195

GTX33195 IHC-P Image

IHC-P analysis of human brain astrocytoma tissue using GTX33195 FCN1 antibody.
Dilution : 1:100

REFERENCE

Application Reference

Zhu G et al. Int Immunopharmacol 2020; 83 : 106473 FCN-A mediates the inflammatory response and the macrophage polarization in Aspergillus fumigatus keratitis of mice by activating the MAPK signaling pathway.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419