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FDPS antibody [HL2123]

Recombinant antibody Orthogonal
Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095
Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095
Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095
Anti-FDPS antibody [HL2123] used in IHC (Paraffin sections) (IHC-P). GTX638095
Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095

Cat. No. GTX638095

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2123

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all FDPS products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human FDPS

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

farnesyl diphosphate synthase , FPPS , FPS , POROK9

Cellular Localization

Cytoplasm

Background

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095

GTX638095 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FDPS antibody [HL2123] (GTX638095) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095

GTX638095 WB Image

Rat tissue extract (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with FDPS antibody [HL2123] (GTX638095) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095

GTX638095 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FDPS antibody [HL2123] (GTX638095) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FDPS antibody [HL2123] used in IHC (Paraffin sections) (IHC-P). GTX638095

GTX638095 IHC-P Image

FDPS antibody [HL2123] detects FDPS protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse tissues.
FDPS stained by FDPS antibody [HL2123] (GTX638095) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FDPS antibody [HL2123] used in Western Blot (WB). GTX638095

GTX638095 WB Image

Orthogonal

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FDPS antibody [HL2123] (GTX638095) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations