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FDPS antibody

Anti-FDPS antibody used in IHC (Paraffin sections) (IHC-P). GTX33196
Anti-FDPS antibody used in Western Blot (WB). GTX33196
Anti-FDPS antibody used in IHC (Paraffin sections) (IHC-P). GTX33196

Cat No. GTX33196

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FDPS (NP_001129293.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

farnesyl diphosphate synthase , FPPS , FPS , POROK9

Cellular Localization

Cytoplasm

Background

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-FDPS antibody used in IHC (Paraffin sections) (IHC-P). GTX33196

GTX33196 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX33196 FDPS antibody.
Dilution : 1:100

Anti-FDPS antibody used in Western Blot (WB). GTX33196

GTX33196 WB Image

WB analysis of various samples using GTX33196 FDPS antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-FDPS antibody used in IHC (Paraffin sections) (IHC-P). GTX33196

GTX33196 IHC-P Image

IHC-P analysis of rat brain tissue using GTX33196 FDPS antibody.
Dilution : 1:100

REFERENCE

There are currently no references for FDPS antibody (GTX33196). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 329