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FEN1 antibody

Anti-FEN1 antibody used in Western Blot (WB). GTX70184

Cat No. GTX70184

Host

Mouse

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
100 μl ($329)

APPLICATION

Application Note

For WB: Use at an assay dependent dilution. Predicted molecular weight: 43 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

43 kDa. ( Note )

Positive Control

MCF7

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant full-length human FEN-1 protein.

Purification

Unpurified
Antiserum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Flap Structure-Specific Endonuclease 1 , Fen-1 , Mf1 , Rad2 , Fen1

Cellular Localization

Nuclear

Background

FEN-1 (Flap EndoNuclease and Five prime Exonuclease) is a 42a protein that functions as an endonuclease when it cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair, and is required in cell-free DNA replication systems.

Database

Research Area

DATA IMAGES

Anti-FEN1 antibody used in Western Blot (WB). GTX70184

GTX70184 WB Image

Detecion of human FEN1 protein in HeLa whole cell lysate using GeneTex polyclonal antiserum GTX70184

REFERENCE

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REVIEW

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Package List Price ($)
$ 329