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FEZ2 antibody

Anti-FEZ2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85422
Anti-FEZ2 antibody used in Western Blot (WB). GTX85422

Cat. No. GTX85422

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all FEZ2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , 3T3 Cell Lysate

Product Note

This antibody is specific for FEZ2 Internal

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

FEZ2 antibody was raised against a 15 amino acid synthetic peptide from near the center of human FEZ2.The immunogen is located within amino acids 160 - 210 of FEZ2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fasciculation and elongation protein zeta 2 , HUM3CL

Background

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

Database

Research Area

DATA IMAGES

Anti-FEZ2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85422

GTX85422 IHC-P Image

IHC-P analysis of human brain tissue using GTX85422 FEZ2 antibody.
Working concentration : 5 μg/ml

Anti-FEZ2 antibody used in Western Blot (WB). GTX85422

GTX85422 WB Image

WB analysis of 3T3 cell lysate using GTX85422 FEZ2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399