APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.1 - 0.2 ug/ml |
0.25 - 0.5 ug/ml |
0.5 - 2.0 ug/ml |
Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human FGF basic
Purification
Affinity chromatography.
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
fibroblast growth factor 2 , BFGF , FGF-2 , FGFB , HBGF-2
Cellular Localization
Secreted , Nucleus
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX17476 IHC-P Image
Staining of formalin fixed, paraffin embedded human breast invasive ductal carcinoma with Rabbit anti Human FGF-basic.
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GTX17476 IHC-P Image
Staining of formalin fixed, paraffin embedded human breast invasive ductal carcinoma with Rabbit anti Human FGF-basic.
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REFERENCE
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REVIEW
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