GeneTex
  • Country / Location Selection

United States (US)

FGFR1 antibody [3D4F7]

Anti-FGFR1 antibody [3D4F7] used in Western Blot (WB). GTX83370

Cat. No. GTX83370

Host

Mouse

Clonality

Monoclonal

Clone Name

3D4F7

Isotype

IgG2b

Application

WB, ELISA

Reactivity

Human
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fibroblast growth factor receptor 1 , BFGFR , CD331 , CEK , ECCL , FGFBR , FGFR-1 , FLG , FLT-2 , FLT2 , HBGFR , HH2 , HRTFDS , KAL2 , N-SAM , OGD , bFGF-R-1

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Nucleus,Cytoplasm, cytosol,Cytoplasmic vesicle

Background

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-FGFR1 antibody [3D4F7] used in Western Blot (WB). GTX83370

GTX83370 WB Image

WB analysis of extracellular domain of human FGFR1 (aa22-376) using GTX83370 FGFR1 antibody [3D4F7].

REFERENCE

There are currently no references for FGFR1 antibody [3D4F7] (GTX83370). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for FGFR1 antibody [3D4F7] (GTX83370). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399