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FGFR2 antibody [JM10-60]

Anti-FGFR2 antibody [JM10-60] used in Western Blot (WB). GTX01004

Cat No. GTX01004

Host

Rabbit

Clonality

Monoclonal

Clone Name

JM10-60

Isotype

IgG

Application

WB

Reactivity

Human
Package
100 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000-1:2000
Not tested in other applications.

Calculated MW

92 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1x TBS (pH7.4), 1% BSA, 40% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fibroblast growth factor receptor 2 , BBDS , BEK , BFR1 , CD332 , CEK3 , CFD1 , ECT1 , FGFR2 , JWS , KGFR , KSAM , TK14 , TK25

Cellular Localization

Cell membrane,Golgi apparatus,Cytoplasmic vesicle,Secreted

Background

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

Database

Research Area

DATA IMAGES

Anti-FGFR2 antibody [JM10-60] used in Western Blot (WB). GTX01004

GTX01004 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FGFR2 antibody [JM10-60] (GTX01004) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
The observed M.W. and the observed expression level are based on the publication: PMID: 30002137.

REFERENCE

There are currently no references for FGFR2 antibody [JM10-60] (GTX01004). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for FGFR2 antibody [JM10-60] (GTX01004). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf