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FGR antibody [6G2]

Anti-FGR antibody [6G2] used in Western Blot (WB). GTX83208
Anti-FGR antibody [6G2] used in IHC (Paraffin sections) (IHC-P). GTX83208

Cat. No. GTX83208

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6G2

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μl ($409)
See all FGR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human FGR expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FGR proto-oncogene, Src family tyrosine kinase , SRC2 , c-fgr , c-src2 , p55-Fgr , p55c-fgr , p58-Fgr , p58c-fgr

Cellular Localization

Cell membrane,Cytoplasm, cytosol,Cytoplasm, cytoskeleton,Mitochondrion inner membrane

Background

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-FGR antibody [6G2] used in Western Blot (WB). GTX83208

GTX83208 WB Image

WB analysis of HL60 (1) Raw264.7 (2) cell lysate using GTX83208 FGR antibody [6G2].

Anti-FGR antibody [6G2] used in IHC (Paraffin sections) (IHC-P). GTX83208

GTX83208 IHC-P Image

IHC-P analysis of human spleen tissue using GTX83208 FGR antibody [6G2].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409