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FHIT antibody [GT1240]

Recombinant antibody
Anti-FHIT antibody [GT1240] used in Western Blot (WB). GTX02837
Anti-FHIT antibody [GT1240] used in Western Blot (WB). GTX02837

Cat. No. GTX02837

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1240

Isotype

 IgG

Application

 WB

Reactivity

 Human, Rat
Package
100 μl ($419)
See all FHIT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

17 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, we recommend adding 50% glycerol, then aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.59 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human FHIT

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fragile histidine triad , AP3Aase , FRA3B

Cellular Localization

Cytoplasm , Mitochondrion , Nucleus

Background

The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-FHIT antibody [GT1240] used in Western Blot (WB). GTX02837

GTX02837 WB Image

Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with FHIT antibody [GT1240] (GTX02837) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FHIT antibody [GT1240] used in Western Blot (WB). GTX02837

GTX02837 WB Image

WB analysis of various samples using GTX02837 FHIT antibody [GT1240].
Dilution : 1:1000
Loading : 25μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 419