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FHIT antibody

Anti-FHIT antibody used in IHC (Paraffin sections) (IHC-P). GTX54037
Anti-FHIT antibody used in IHC (Paraffin sections) (IHC-P). GTX54037
Anti-FHIT antibody used in Western Blot (WB). GTX54037

Cat. No. GTX54037

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all FHIT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

17 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-147 of human FHIT (NP_001159715.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fragile histidine triad , AP3Aase , FRA3B

Cellular Localization

Cytoplasm,Mitochondrion,Nucleus

Background

The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-FHIT antibody used in IHC (Paraffin sections) (IHC-P). GTX54037

GTX54037 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX54037 FHIT antibody.
Dilution : 1:100

Anti-FHIT antibody used in IHC (Paraffin sections) (IHC-P). GTX54037

GTX54037 IHC-P Image

IHC-P analysis of rat heart tissue using GTX54037 FHIT antibody.
Dilution : 1:100

Anti-FHIT antibody used in Western Blot (WB). GTX54037

GTX54037 WB Image

WB analysis of various sample lysates using GTX54037 FHIT antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399