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FKBP12 antibody [GT1281]

Recombinant antibody
Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193
Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193
Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193
Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193
Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

Cat. No. GTX03193

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1281

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($439)
See all FKBP12 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.85 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human FKBP12.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FKBP prolyl isomerase 1A , FKBP-12 , FKBP-1A , FKBP1 , FKBP12 , PKC12 , PKCI2 , PPIASE

Cellular Localization

Cytoplasm, cytosol

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES

Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

GTX03193 WB Image

Whole cell extract (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with FKBP12 antibody [GT1281] (GTX03193) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

GTX03193 WB Image

Various tissue extracts (50 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with FKBP12 antibody [GT1281] (GTX03193) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

GTX03193 WB Image

Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with FKBP12 antibody [GT1281] (GTX03193) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

GTX03193 WB Image

WB analysis of various samples using GTX03193 FKBP12 antibody [GT1281].
Dilution : 1:1000
Loading : 25μg per lane

Anti-FKBP12 antibody [GT1281] used in Western Blot (WB). GTX03193

GTX03193 WB Image

WB analysis of U251-MG whole cell lysate using GTX03193 FKBP12 antibody [GT1281].
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 439