GeneTex
United States (US)

FKBP4 antibody

GTX64678_20180530_IHC-P_3_18121411_179.jpg
GTX64678_20180530_IHC-P_18121411_138.jpg
GTX64678_20180530_IHC-P_6_18121411_489.jpg
GTX64678_20180530_WB_18121411_758.jpg
GTX64678_20180530_IHC-P_1_18121411_335.jpg
GTX64678_20180530_IHC-P_2_18121411_880.jpg
GTX64678_20180530_ICCIF_18121411_326.jpg
GTX64678_20180530_IHC-P_4_18121411_768.jpg
GTX64678_20180530_IHC-P_5_18121411_228.jpg
GTX64678_20180530_IP_18121411_973.jpg

Cat No. GTX64678

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IP
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:200
IP 1:50 - 1:200
Not tested in other applications.

Calculated MW

52 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 220-459 of human FKBP4 (NP_002005.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PPIASE Antibody , HSP56 Antibody , FKBP52 Antibody , FKBP59 Antibody , P52 Antibody , HBI Antibody , FKBP51 Antibody

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES
GTX64678_20180530_IHC-P_3_18121411_179.jpg

GTX64678 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX64678 FKBP4 antibody.
Dilution : 1:100

GTX64678_20180530_IHC-P_18121411_138.jpg

GTX64678 IHC-P Image

IHC-P analysis of human adenomyosis tissue using GTX64678 FKBP4 antibody.
Dilution : 1:100

GTX64678_20180530_IHC-P_6_18121411_489.jpg

GTX64678 IHC-P Image

IHC-P analysis of human uterus leiomyoma tissue using GTX64678 FKBP4 antibody.
Dilution : 1:200

GTX64678_20180530_WB_18121411_758.jpg

GTX64678 WB Image

WB analysis of various samples using GTX64678 FKBP4 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64678_20180530_IHC-P_1_18121411_335.jpg

GTX64678 IHC-P Image

IHC-P analysis of human adenomyosis tissue using GTX64678 FKBP4 antibody.
Dilution : 1:200

GTX64678_20180530_IHC-P_2_18121411_880.jpg

GTX64678 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX64678 FKBP4 antibody.
Dilution : 1:200

GTX64678_20180530_ICCIF_18121411_326.jpg

GTX64678 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX64678 FKBP4 antibody.
Blue : DAPI

GTX64678_20180530_IHC-P_4_18121411_768.jpg

GTX64678 IHC-P Image

IHC-P analysis of human liver injury tissue using GTX64678 FKBP4 antibody.
Dilution : 1:200

GTX64678_20180530_IHC-P_5_18121411_228.jpg

GTX64678 IHC-P Image

IHC-P analysis of human uterus leiomyoma tissue using GTX64678 FKBP4 antibody.
Dilution : 1:100

GTX64678_20180530_IP_18121411_973.jpg

GTX64678 IP Image

IP analysis of 293T cell lysate using GTX64678 FKBP4 antibody.
IP reaction : 1μg antibody / 200μg cell lysate
Dilution : 1:1000

Package List Price ($)
$ 319