Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.02% Sodium azide
Storage
Store the peptide at -20ºC, stable for one year.
Concentration
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
Casp8 And Fadd Like Apoptosis Regulator , Cash , Casp8Ap1 , Clarp , Casper , Flame , Flame-1 , Flame1 , Flip , I-Flice , Mrit , C-Flip , C-Flipl , C-Flipr , C-Flips , Cflar
Background
The human homolog of viral FLIP has four splice variants known as FLIP alpha, Beta, gamma and kappa. These are FLICE inhibitory proteins also known as Casper, I-FLICE, FLAME-1, CASH, CLARP and Usurpin. They contain two death effector domains and one caspase domain. FLIP interacts with FADD, caspase-8 and 10 to inhibit apoptosis initiated by Fas, TNF-R1 and TRAIL-R.
Research Area