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FLT3 antibody [9G23]

Anti-FLT3 antibody [9G23] used in Western Blot (WB). GTX52747

Cat No. GTX52747

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 9G23

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
100 μg ($329)
See all FLT3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Flt-3

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD135 , FLK2 , FLT3 , STK1 , fms related tyrosine kinase 3

Cellular Localization

Membrane,Endoplasmic reticulum lumen

Background

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-FLT3 antibody [9G23] used in Western Blot (WB). GTX52747

GTX52747 WB Image

WB analysis of human placenta tissue lysate using GTX52747 FLT3 antibody [9G23].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 329