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FLT3 antibody [BV10A4]

Cat No. GTX80208

Host

Mouse

Clonality

Monoclonal

Clone Name

BV10A4

Isotype

IgG1

Application

FACS, IP

Reactivity

Human
Package
100 μg ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

Specificity/Sensitivity

We do not recommend use of this product for Mouse.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

BV-173 leukemic cell line

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD135 , FLK2 , FLT3 , STK1 , fms related tyrosine kinase 3

Cellular Localization

Membrane,Endoplasmic reticulum lumen

Background

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

Database

Research Area

REFERENCE

There are currently no references for FLT3 antibody [BV10A4] (GTX80208). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 289