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FMRP antibody

Anti-FMRP antibody used in IHC (Paraffin sections) (IHC-P). GTX31911
Anti-FMRP antibody used in Western Blot (WB). GTX31911
Anti-FMRP antibody used in IHC (Paraffin sections) (IHC-P). GTX31911

Cat No. GTX31911

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

FMRP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FMRP.The immunogen is located within the last 50 amino acids of FMRP.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fragile X mental retardation 1 , FMRP , FRAXA , POF , POF1

Cellular Localization

Nucleus,Cytoplasm,Cell projection, dendrite,Cell junction, synapse,Cell membrane,Nucleolus

Background

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-FMRP antibody used in IHC (Paraffin sections) (IHC-P). GTX31911

GTX31911 IHC-P Image

IHC-P analysis of human brain tissue using GTX31911 FMRP antibody.
Working concentration : 2.5 μg/ml

Anti-FMRP antibody used in Western Blot (WB). GTX31911

GTX31911 WB Image

WB analysis of rat brain tissue lysate using GTX31911 FMRP antibody.
Working concentration : 1 μg/ml

Anti-FMRP antibody used in IHC (Paraffin sections) (IHC-P). GTX31911

GTX31911 IHC-P Image

IHC-P analysis of human brain tissue using GTX31911 FMRP antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339