Phosphate-buffered saline, pH 7.4, containing no preservatives
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Amino acids 242-655 of FKHR expressed in E. coli.
Protein G purified
From tissue culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Forkhead Box O1 , Fkh1 , Fkhr , Foxo1A , Foxo1
FKHR-14E4 recognizes FKHR (ForKHead in Rhabdomyosarcoma), a 70a protein, which is one member in a subfamily of the forkhead homeotic gene family of transcription factors. Recent experiments have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein.