FOXO3A (phospho Ser253) antibody

Cat. No. GTX79072

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse
Package	100 μg ($399)

See all FOXO3A products

Datasheet

View product citations for antibody GTX79072 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500 - 1:1000
IHC-P	1:50 - 1:100

Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human FOXO3A around the phosphorylation site of serine 253 (A-V-Sp-M-D).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

RRID

AB_11178165

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3,FOXO3A,forkhead box O3

Cellular Localization

Cytoplasm,Cytosol,Nucleus

Background

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Database

Gene ID: 2309 FOXO3
UniProt: O43524 FOXO3

Research Area

DATA IMAGES

GTX79072 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX79072 FOXO3A (phospho Ser253) antibody.

GTX79072 WB Image

WB analysis of NIH/3T3 cells treated with serum lysate using GTX79072 FOXO3A (phospho Ser253) antibody.
Left : Primary antibody
Right : Primary antibody preincubated with immunogen peptide

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 399

Qty