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FREM2 antibody

Anti-FREM2 antibody used in Western Blot (WB). GTX85004
Anti-FREM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85004
Anti-FREM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85004

Cat. No. GTX85004

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all FREM2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

351 kDa. ( Note )

Positive Control

A-20 Cell Slide(GTX25541) , A20 Cell Lysate(GTX27180)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2.The immunogen is located within amino acids 1920 - 1970 of FREM2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FRAS1 related extracellular matrix protein 2 , FRASRS2

Cellular Localization

Cell membrane

Background

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.

Database

Research Area

DATA IMAGES

Anti-FREM2 antibody used in Western Blot (WB). GTX85004

GTX85004 WB Image

WB analysis of A-20 cell lysate using GTX85004 FREM2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-FREM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85004

GTX85004 ICC/IF Image

ICC/IF analysis of A-20 cells using GTX85004 FREM2 antibody.
Working concentration : 20 μg/ml

Anti-FREM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85004

GTX85004 ICC/IF Image

ICC/IF analysis of A-20 cells using GTX85004 FREM2 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399