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FYN (phospho Tyr530) antibody

Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757
Anti-FYN (phospho Tyr530) antibody used in IHC (Paraffin sections) (IHC-P). GTX86757
Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757
Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757

Cat. No. GTX86757

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($409)
See all FYN products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store at -20 degrees Celcius. Product is stable for at least 1 year.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530.

Purification

Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FYN proto-oncogene, Src family tyrosine kinase , SLK , SYN , p59-FYN

Cellular Localization

Present and active in lipid rafts. Present in cell body and along the process of mature and developing oligodendroyctes.

Background

Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.

Database

Research Area

DATA IMAGES

Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757

GTX86757 WB Image

WB analysis of 293 cells treated with H₂O₂ 100uM 15 mins lysates GTX86757 Fyn (phospho Tyr530) antibody. The lane on the right is blocked with the phospho peptide.

Anti-FYN (phospho Tyr530) antibody used in IHC (Paraffin sections) (IHC-P). GTX86757

GTX86757 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX86757 Fyn (phospho Tyr530) antibody. The picture on the right is blocked with the phospho peptide.

Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757

GTX86757 WB Image

WB analysis of 3T3 cell lysates using GTX86757 Fyn (phospho Tyr530) antibody.
Dilution : 1:2000

Anti-FYN (phospho Tyr530) antibody used in Western Blot (WB). GTX86757

GTX86757 WB Image

WB analysis of LOVO+UV cell lysates using GTX86757 Fyn (phospho Tyr530) antibody.
Dilution : 1:2000

REFERENCE

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REVIEW

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Package List Price ($)
$ 409