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Factor H antibody [10-10]

Cat. No. GTX41630

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10-10

Isotype

 IgG1

Application

 WB, IHC-Fr, FACS, ELISA

Reactivity

 Human
Package
100 μg ($579)
See all Factor H products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

139 kDa. ( Note )

Product Note

This antibody recognises human complement factor H which exists in 2 forms. The most common form, of 150 kDa, and the less common form of 43 kDa.

PROPERTIES

Form

Liquid

Buffer

Borate buffered saline

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human complement factor H from serum.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement factor H , AHUS1 , AMBP1 , ARMD4 , ARMS1 , CFHL3 , FH , FHL1 , HF , HF1 , HF2 , HUS

Cellular Localization

Secreted

Background

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 579