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Factor H antibody [N3C1], Internal

Anti-Factor H antibody [N3C1], Internal used in Western Blot (WB). GTX100305
Anti-Factor H antibody [N3C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX100305

Cat. No. GTX100305

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Factor H products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:10000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

139 kDa. ( Note )

Positive Control

human plasma

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Factor H. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1240643

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement factor H , AHUS1 , AMBP1 , ARMD4 , ARMS1 , CFHL3 , FH , FHL1 , HF , HF1 , HF2 , HUS

Cellular Localization

Secreted

Background

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Factor H antibody [N3C1], Internal used in Western Blot (WB). GTX100305

GTX100305 WB Image

Human tissue extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Factor H antibody [N3C1], Internal (GTX100305) diluted at 1:500.

Anti-Factor H antibody [N3C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX100305

GTX100305 IHC-P Image

Immunohistochemical analysis of paraffin-embedded U373 xenograft, using Factor H(GTX100305) antibody at 1:200 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169