GeneTex

  • Country / Location Selection

United States (US)

Factor H antibody [OX-23]

Cat. No. GTX41629

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 OX-23

Isotype

 IgG1

Application

 WB, IP, ELISA, RIA

Reactivity

 Human, Mouse
Package
200 μg ($459)
See all Factor H products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IP Assay dependent
ELISA 1/50-1/200
RIA Assay dependent
Not tested in other applications.

Calculated MW

139 kDa. ( Note )

Product Note

This antibody recognizes a 43-49kD truncated form of factor H present at low level (1-5ug/ml) in plasma and urine.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human complement factor H.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement factor H , AHUS1 , AMBP1 , ARMD4 , ARMS1 , CFHL3 , FH , FHL1 , HF , HF1 , HF2 , HUS

Cellular Localization

Secreted

Background

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Database

Research Area

REFERENCE

There are currently no references for Factor H antibody [OX-23] (GTX41629). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Factor H antibody [OX-23] (GTX41629). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459