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Factor IX antibody

Anti-Factor IX antibody used in IHC (Paraffin sections) (IHC-P). GTX55612
Anti-Factor IX antibody used in IHC (Paraffin sections) (IHC-P). GTX55612
Anti-Factor IX antibody used in Western Blot (WB). GTX55612

Cat. No. GTX55612

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Factor IX products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human F9 (NP_000124.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887932

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

coagulation factor IX , F9 p22 , FIX , HEMB , P19 , PTC , THPH8

Cellular Localization

Secreted

Background

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Factor IX antibody used in IHC (Paraffin sections) (IHC-P). GTX55612

GTX55612 IHC-P Image

IHC-P analysis of human placenta tissue using GTX55612 Factor IX antibody.
Blue : DAPI
Dilution : 1:100

Anti-Factor IX antibody used in IHC (Paraffin sections) (IHC-P). GTX55612

GTX55612 IHC-P Image

IHC-P analysis of rat liver tissue using GTX55612 Factor IX antibody.
Blue : DAPI
Dilution : 1:100

Anti-Factor IX antibody used in Western Blot (WB). GTX55612

GTX55612 WB Image

WB analysis of human plasma lysate using GTX55612 Factor IX antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Yang L et al. Oncotarget 2018; 9 (5) : 5614-5626 Anticoagulants inhibit proteolytic clearance of plasma amyloid beta.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399