GeneTex
United States (US)

Factor VIII antibody

GTX34370_20170112_WB_18121410_138.jpg
GTX34370_20170112_WB_1_18121410_592.jpg

Cat No. GTX34370

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA, IHC
Reactivity Human, Mouse
APPLICATION

Calculated MW

267 kDa. ( Note )

Specificity/Sensitivity

Factor VIII Polyclonal Antibody detects endogenous levels of Factor VIII protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from the C-terminal region of human Factor VIII at AA range: 2130-2210.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Coagulation Factor Viii,Ahf,Dxs1253E,F8B,F8C,Fviii,Hema,F8

Background

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX34370_20170112_WB_18121410_138.jpg

GTX34370 WB Image

Western Blot (WB) analysis of specific cells using Factor VIII Polyclonal Antibody.

GTX34370_20170112_WB_1_18121410_592.jpg

GTX34370 WB Image

Western Blot (WB) analysis of HuvEc cells using Factor VIII Polyclonal Antibody.

Package List Price ($)
$ 319