GeneTex
  • Country / Location Selection

United States (US)

Factor XI antibody [7C38]

Cat No. GTX52646

Host

Mouse

Clonality

Monoclonal

Clone Name

7C38

Isotype

IgG2

Application

WB, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Factor XI.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

F11 , FXI , coagulation factor XI , Factor XI

Cellular Localization

Secreted

Background

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for Factor XI antibody [7C38] (GTX52646). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Factor XI antibody [7C38] (GTX52646). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329