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Fas Ligand antibody [1Z20]

Cat No. GTX52721

Host

Mouse

Clonality

Monoclonal

Clone Name

1Z20

Isotype

IgG1

Application

WB

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TNFSF6 EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ALPS1B , APT1LG1 , APTL , CD178 , CD95L , FASL , FASLG , Fas ligand , TNFSF6 , TNLG1A , fasL , Fas Ligand , Fasligand , CD95 ligand

Cellular Localization

Cell membrane,Cytoplasmic vesicle lumen,Lysosome lumen,Secreted,Nucleus

Background

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Database

Research Area

REFERENCE

There are currently no references for Fas Ligand antibody [1Z20] (GTX52721). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Fas Ligand antibody [1Z20] (GTX52721). Be the first to share your experience with this product.
SDS
PBS.pdf