Summary
The MFL3 monoclonal antibody reacts with mouse CD178, a 40 kD member type-II transmembrane protein and member of the TNF family of proteins. CD178 is also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. CD178 is expressed on activated T cells and and natural killer (NK) cells and also tissue at immune privileged sites such as the eye and testis. FasL interacts with its receptor CD95 (Fas) to initiate apoptotic cell death and is thought to play a role in T cell development, immune response regulation, and cell-mediated cytotoxic responses. This MFL3 clone has been reported to block CD178/CD96 induced apoptosis.
Form
Liquid
Buffer
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Purification
Purified by affinity chromatography
From tissue culture supernatant
Conjugation
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.