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Fas Ligand antibody [MFL3] (PE)

Anti-Fas Ligand antibody [MFL3] (PE) used in Flow cytometry (FACS). GTX01516-08

Cat. No. GTX01516-08

Host

Armenian Hamster

Clonality

Monoclonal

Clone Name

MFL3

Isotype

IgG

Application

FACS

Reactivity

Mouse
Package
100 μg ($229)
PRODUCT

Summary

The MFL3 monoclonal antibody reacts with mouse CD178, a 40 kD member type-II transmembrane protein and member of the TNF family of proteins. CD178 is also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. CD178 is expressed on activated T cells and and natural killer (NK) cells and also tissue at immune privileged sites such as the eye and testis. FasL interacts with its receptor CD95 (Fas) to initiate apoptotic cell death and is thought to play a role in T cell development, immune response regulation, and cell-mediated cytotoxic responses. This MFL3 clone has been reported to block CD178/CD96 induced apoptosis.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Not tested in other applications.

Calculated MW

0|31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane,Cytoplasmic vesicle lumen,Lysosome lumen,Secreted,Nucleus

Database

Research Area

DATA IMAGES

Anti-Fas Ligand antibody [MFL3] (PE) used in Flow cytometry (FACS). GTX01516-08

GTX01516-08 FACS Image

FACS analysis of mouse Fas Ligand transfected cells using GTX01516-08 Fas Ligand antibody [MFL3] (PE).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 229