Fas Ligand antibody [NOK-1]

Cat. No. GTX01476
Cat. No.  GTX01476
This Fas Ligand antibody [NOK-1] (GTX01476) is a mouse monoclonal antibody validated for detection of Fas Ligand by WB, FCM, IP, ELISA, and Neutralizing /Inhibition. Reactivity has been shown in Human.
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    NOK-1
  • Isotype
    IgG1
  • Applications
    WB FCM IP ELISA Neutralizing /Inhibition
  • Reactivity
    Human
Summary
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
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