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Fas Ligand antibody

Anti-Fas Ligand antibody used in IHC (Paraffin sections) (IHC-P). GTX66619
Anti-Fas Ligand antibody used in Western Blot (WB). GTX66619

Cat. No. GTX66619

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Fas Ligand products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 100-150 of Human FasL.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Fas ligand , ALPS1B , APT1LG1 , APTL , CD178 , CD95-L , CD95L , FASL , TNFSF6 , TNLG1A

Cellular Localization

Cell membrane

Background

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-Fas Ligand antibody used in IHC (Paraffin sections) (IHC-P). GTX66619

GTX66619 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66619 Fas Ligand antibody.
Dilution : 1:100

Anti-Fas Ligand antibody used in Western Blot (WB). GTX66619

GTX66619 WB Image

WB analysis of various samples using GTX66619 Fas Ligand antibody.
Lane1 : Hela whole cell lysate
Lane2 : NIH-3T3 whole cell lysate
Lane3 : PC12 whole cell lysate
Dilution : 1:500

REFERENCE

Application Reference

Su CC et al. Nutrients 2023; 15 (23) Protective Effect of Alpha-Linolenic Acid on Human Oral Squamous Cell Carcinoma Metastasis and Apoptotic Cell Death.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399