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Fascin 1 antibody [IM20]

Anti-Fascin 1 antibody [IM20] used in IHC (Paraffin sections) (IHC-P). GTX01968

Cat. No. GTX01968

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IM20

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
500 μl ($489)
See all Fascin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100–1:200
IHC-P 1:200–1:400

Note :

IHC-P
High temperature antigen unmasking technique. Standard ABC technique.
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the C-terminal region of the fascin molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fascin actin-bundling protein 1 , FAN1 , HSN , SNL , p55

Cellular Localization

Cytoplasm, cytosol , Cytoplasm, cytoskeleton , Cell junction

Background

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-Fascin 1 antibody [IM20] used in IHC (Paraffin sections) (IHC-P). GTX01968

GTX01968 IHC-P Image

IHC-P analysis of hodgkin's lymphoma tissue using GTX01968 Fascin 1 antibody [IM20].

REFERENCE

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REVIEW

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Package List Price ($)
$ 489