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FcRn heavy chain heterodimer antibody [1G3]

Cat. No. GTX14550

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1G3

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA

Reactivity

 Rat, Bovine
Package
500 μg ($399)
See all FcRn heavy chain heterodimer products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Purified soluble FcRn

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

RRID

AB_2887516

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane

Background

binds and transports maternal immunoglobulin gamma from milk; plays a role in providing maternal immunity to neonates [RGD, Feb 2006]

Database

Research Area

REFERENCE

Application Reference

Garc?a-Serra A et al. Neurol Neuroimmunol Neuroinflamm 2021; 8 (6) Blocking Placental Class G Immunoglobulin Transfer Prevents NMDA Receptor Antibody Effects in Newborn Mice.
Deissler HL et al. Exp Eye Res 2016; 154 : 39-46 Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells.
Application : WB
Reactivity : Bovine
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Package List Price ($)
$ 399